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ALFA-PRF: a novel approach to detect murine perforin release from CTLs into the immune synapse

When killing through the granule exocytosis pathway, cytotoxic lymphocytes release key effector molecules into the immune synapse, perforin and granzymes, to initiate target cell killing. The pore-forming perforin is essential for the function of cytotoxic lymphocytes, as its pores disrupt the targe...

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Detalles Bibliográficos
Autores principales:	Rudd-Schmidt, Jesse A., Laine, Romain F., Noori, Tahereh, Brennan, Amelia J., Voskoboinik, Ilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813862/ https://www.ncbi.nlm.nih.gov/pubmed/36618385 http://dx.doi.org/10.3389/fimmu.2022.931820

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