Metabolism heterogeneity in melanoma fuels deactivation of immunotherapy: Predict before protect

Malignant melanoma is widely acknowledged as the most lethal skin malignancy. The metabolic reprogramming in melanoma leads to alterations in glycolysis and oxidative phosphorylation (OXPHOS), forming a hypoxic, glucose-deficient and acidic tumor microenvironment which inhibits the function of immun...

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Detalles Bibliográficos
Autores principales: Zhang, Xinyue, Tai, Zongguang, Miao, Fengze, Huang, Hao, Zhu, Quangang, Bao, Leilei, Chen, Zhongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813867/
https://www.ncbi.nlm.nih.gov/pubmed/36620597
http://dx.doi.org/10.3389/fonc.2022.1046102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813867/
https://www.ncbi.nlm.nih.gov/pubmed/36620597
http://dx.doi.org/10.3389/fonc.2022.1046102

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