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The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis
Background In this study, we evaluated neutrophil-to-lymphocyte ratio (NLR) values and abdominal computed tomography (CT) scans in preoperative patients of acute cholecystitis (AC) and their significance in differentiating between severe and non-severe conditions. This study will help further in-dep...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cureus
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813872/ https://www.ncbi.nlm.nih.gov/pubmed/36620833 http://dx.doi.org/10.7759/cureus.32243 |
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author | Prakash, Gayathri Hasan, Mohammad |
author_facet | Prakash, Gayathri Hasan, Mohammad |
author_sort | Prakash, Gayathri |
collection | PubMed |
description | Background In this study, we evaluated neutrophil-to-lymphocyte ratio (NLR) values and abdominal computed tomography (CT) scans in preoperative patients of acute cholecystitis (AC) and their significance in differentiating between severe and non-severe conditions. This study will help further in-depth investigation on both of these diagnostic modalities and timely assess severe AC to avoid the worst prognosis. Methodology This single-center, cross-sectional study was conducted at Government Villupuram Medical College from July 2021 to January 2022. We enrolled patients aged >18 years diagnosed with AC. The demographic variables and clinical features of the enrolled patients were collected. All enrolled patients were divided into two categories (severe or non-severe AC) based on the pathological and clinical findings. The data were collected and entered in SPSS Statistics version 26 (IBM Corp., Armonk, NY, USA). The variation between the severe and non-severe AC groups was compared using Student’s t-test to analyze continuous variables. The chi-square test was used to evaluate the association between the categorical variables. A p-value of <0.05 was considered significant. Results Among patients with severe AC, 29 (72.5%) were female, 29 (72.5%) were aged >50 years, 34 (85%) were alcoholics, and 26 (65%) were smokers. In patients with severe AC, the mean for NLR was 18.6500 ± 2.32655. On CT scans, 29 (72.5%) patients showed gallbladder distension, 31 (77.5%) showed increased pericholecystic fat stranding, and 18 (45%) showed pericholecystic fluid collection. CT scan findings and NLR values were significantly associated. Conclusions Gallbladder distension, increased pericholecystic fat stranding, and pericholecystic fluid collection on abdominal CT scan along with raised NLR are significant findings associated with assessing the severity of AC. Therefore, both testing modalities (CT scan and NLR) should be utilized together in hospitals to achieve better outcomes for AC and avoid complications. |
format | Online Article Text |
id | pubmed-9813872 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-98138722023-01-06 The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis Prakash, Gayathri Hasan, Mohammad Cureus Radiology Background In this study, we evaluated neutrophil-to-lymphocyte ratio (NLR) values and abdominal computed tomography (CT) scans in preoperative patients of acute cholecystitis (AC) and their significance in differentiating between severe and non-severe conditions. This study will help further in-depth investigation on both of these diagnostic modalities and timely assess severe AC to avoid the worst prognosis. Methodology This single-center, cross-sectional study was conducted at Government Villupuram Medical College from July 2021 to January 2022. We enrolled patients aged >18 years diagnosed with AC. The demographic variables and clinical features of the enrolled patients were collected. All enrolled patients were divided into two categories (severe or non-severe AC) based on the pathological and clinical findings. The data were collected and entered in SPSS Statistics version 26 (IBM Corp., Armonk, NY, USA). The variation between the severe and non-severe AC groups was compared using Student’s t-test to analyze continuous variables. The chi-square test was used to evaluate the association between the categorical variables. A p-value of <0.05 was considered significant. Results Among patients with severe AC, 29 (72.5%) were female, 29 (72.5%) were aged >50 years, 34 (85%) were alcoholics, and 26 (65%) were smokers. In patients with severe AC, the mean for NLR was 18.6500 ± 2.32655. On CT scans, 29 (72.5%) patients showed gallbladder distension, 31 (77.5%) showed increased pericholecystic fat stranding, and 18 (45%) showed pericholecystic fluid collection. CT scan findings and NLR values were significantly associated. Conclusions Gallbladder distension, increased pericholecystic fat stranding, and pericholecystic fluid collection on abdominal CT scan along with raised NLR are significant findings associated with assessing the severity of AC. Therefore, both testing modalities (CT scan and NLR) should be utilized together in hospitals to achieve better outcomes for AC and avoid complications. Cureus 2022-12-06 /pmc/articles/PMC9813872/ /pubmed/36620833 http://dx.doi.org/10.7759/cureus.32243 Text en Copyright © 2022, Prakash et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiology Prakash, Gayathri Hasan, Mohammad The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title | The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title_full | The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title_fullStr | The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title_full_unstemmed | The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title_short | The Accuracy of Neutrophil-to-Lymphocyte Ratio and Abdominal Computed Tomography to Predict the Severity of Acute Cholecystitis |
title_sort | accuracy of neutrophil-to-lymphocyte ratio and abdominal computed tomography to predict the severity of acute cholecystitis |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813872/ https://www.ncbi.nlm.nih.gov/pubmed/36620833 http://dx.doi.org/10.7759/cureus.32243 |
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