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Adeno-associated virus vector intraperitoneal injection induces colonic mucosa and submucosa transduction and alters the diversity and composition of the faecal microbiota in rats

BACKGROUND: Viral vector technology, especially recombinant adeno-associated virus vector (rAAV) technology, has shown great promise in preclinical research for clinical applications. Several studies have confirmed that rAAV can successfully transduce the enteric nervous system (ENS), and rAAV gene...

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Detalles Bibliográficos
Autores principales:	Ma, Li-Tian, Lian, Jing-Xuan, Bai, Yang, Shang, Meng-Juan, Zhang, Zhe-Zhe, Wu, Fei-Fei, Chen, Jing, Meng, Xian-Bo, Zheng, Jin, Li, Tian, Li, Yun-Qing, Wang, Jing-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813966/ https://www.ncbi.nlm.nih.gov/pubmed/36619753 http://dx.doi.org/10.3389/fcimb.2022.1028380

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