Towards the catalytic activation of inert small molecules by main-group ambiphiles

The activation of very inert small molecules generally requires highly reactive activating species, but the high energy of these species makes their regeneration, and thus also catalytic turnover of the reaction, difficult to achieve. Here, the authors highlight the formidable challenge of overcomin...

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Autores principales: Dewhurst, Rian D., Légaré, Marc-André, Braunschweig, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814040/
https://www.ncbi.nlm.nih.gov/pubmed/36703344
http://dx.doi.org/10.1038/s42004-020-00371-4
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author Dewhurst, Rian D.
Légaré, Marc-André
Braunschweig, Holger
author_facet Dewhurst, Rian D.
Légaré, Marc-André
Braunschweig, Holger
author_sort Dewhurst, Rian D.
collection PubMed
description The activation of very inert small molecules generally requires highly reactive activating species, but the high energy of these species makes their regeneration, and thus also catalytic turnover of the reaction, difficult to achieve. Here, the authors highlight the formidable challenge of overcoming the tradeoff between activating power and catalytic turnover in the context of main-group ambiphiles.
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spelling pubmed-98140402023-01-10 Towards the catalytic activation of inert small molecules by main-group ambiphiles Dewhurst, Rian D. Légaré, Marc-André Braunschweig, Holger Commun Chem Comment The activation of very inert small molecules generally requires highly reactive activating species, but the high energy of these species makes their regeneration, and thus also catalytic turnover of the reaction, difficult to achieve. Here, the authors highlight the formidable challenge of overcoming the tradeoff between activating power and catalytic turnover in the context of main-group ambiphiles. Nature Publishing Group UK 2020-09-16 /pmc/articles/PMC9814040/ /pubmed/36703344 http://dx.doi.org/10.1038/s42004-020-00371-4 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Dewhurst, Rian D.
Légaré, Marc-André
Braunschweig, Holger
Towards the catalytic activation of inert small molecules by main-group ambiphiles
title Towards the catalytic activation of inert small molecules by main-group ambiphiles
title_full Towards the catalytic activation of inert small molecules by main-group ambiphiles
title_fullStr Towards the catalytic activation of inert small molecules by main-group ambiphiles
title_full_unstemmed Towards the catalytic activation of inert small molecules by main-group ambiphiles
title_short Towards the catalytic activation of inert small molecules by main-group ambiphiles
title_sort towards the catalytic activation of inert small molecules by main-group ambiphiles
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814040/
https://www.ncbi.nlm.nih.gov/pubmed/36703344
http://dx.doi.org/10.1038/s42004-020-00371-4
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