Cargando…
The making of a potent L-lactate transport inhibitor
L-lactate is an important metabolite, energy source, and signaling molecule in health and disease. In mammals, its transport across biological membranes is mediated by monocarboxylate transporters (MCTs) of the solute carrier 16 (SLC16) family. Malfunction, overexpression or absence of transporters...
Autores principales: | Bosshart, Patrick D., Kalbermatter, David, Bonetti, Sara, Fotiadis, Dimitrios |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814091/ https://www.ncbi.nlm.nih.gov/pubmed/36697570 http://dx.doi.org/10.1038/s42004-021-00564-5 |
Ejemplares similares
-
Structure and function of a monocarboxylate transporter homolog specific for L-lactate
por: Bosshart, Patrick D., et al.
Publicado: (2019) -
Mechanistic basis of L-lactate transport in the SLC16 solute carrier family
por: Bosshart, Patrick D., et al.
Publicado: (2019) -
Protein-enriched outer membrane vesicles as a native platform for outer membrane protein studies
por: Thoma, Johannes, et al.
Publicado: (2018) -
A procedure and double-chambered device for macromolecular crystal flash-cooling in different cryogenic liquids
por: Jeckelmann, Jean-Marc, et al.
Publicado: (2020) -
High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding
por: Ilgü, Hüseyin, et al.
Publicado: (2021)