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Bayesian optimization-driven parallel-screening of multiple parameters for the flow synthesis of biaryl compounds

Traditional optimization methods using one variable at a time approach waste time and chemicals and assume that different parameters are independent from one another. Hence, a simpler, more practical, and rapid process for predicting reaction conditions that can be applied to several manufacturing e...

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Detalles Bibliográficos
Autores principales: Kondo, Masaru, Wathsala, H. D. P., Salem, Mohamed S. H., Ishikawa, Kazunori, Hara, Satoshi, Takaai, Takayuki, Washio, Takashi, Sasai, Hiroaki, Takizawa, Shinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814103/
https://www.ncbi.nlm.nih.gov/pubmed/36698029
http://dx.doi.org/10.1038/s42004-022-00764-7