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Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling

Marginal zone (MZ) B cells represent innate-like B cells that mediate a fast immune response. The adhesion of MZ B cells to the marginal sinus of the spleen is governed by integrins. Here, we address the question of whether β1-integrin has additional functions by analyzing Itgb1(fl/fl)CD21(Cre) mice...

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Detalles Bibliográficos
Autores principales:	Andreani, Virginia, Ramamoorthy, Senthilkumar, Fässler, Reinhard, Grosschedl, Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814157/ https://www.ncbi.nlm.nih.gov/pubmed/36350325 http://dx.doi.org/10.1084/jem.20220342

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