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Platelet-derived TLT-1 promotes tumor progression by suppressing CD8(+) T cells

Current understanding of tumor immunosuppressive mechanisms forms the basis for modern day immunotherapies. Immunoregulatory role of platelets in cancer remains largely elusive. Platelets from non-small cell lung cancer (NSCLC) patients revealed a distinct activation phenotype. TREM-like transcript...

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Detalles Bibliográficos
Autores principales: Tyagi, Tarun, Jain, Kanika, Yarovinsky, Timur O., Chiorazzi, Michael, Du, Jing, Castro, Cecilia, Griffin, Jules, Korde, Asawari, Martin, Kathleen A., Takyar, Shervin S., Flavell, Richard A., Patel, Abhijit A., Hwa, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814191/
https://www.ncbi.nlm.nih.gov/pubmed/36305874
http://dx.doi.org/10.1084/jem.20212218