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Non-enzymatic catalytic asymmetric cyanation of acylsilanes

The asymmetric cyanation of acylsilanes affords densely functionalized tetrasubstituted chiral carbon centers bearing silyl, cyano, and hydroxy groups, which are of particular interest in synthetic and medicinal chemistry. However, this method has been limited to a few enzymatic approaches, which em...

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Detalles Bibliográficos
Autores principales: Nagano, Tagui, Matsumoto, Akira, Yoshizaki, Ryotaro, Asano, Keisuke, Matsubara, Seijiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814240/
https://www.ncbi.nlm.nih.gov/pubmed/36697739
http://dx.doi.org/10.1038/s42004-022-00662-y