Selenium-containing small molecules

The role of selenium in proteins and nucleic acids is well-established, but the pathway for incorporating selenium into small molecules remains unknown. Now, using bioinformatics tools, a selenium-incorporating gene cluster is discovered from immense genomic data, leading to the identification of se...

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Detalles Bibliográficos
Autor principal: Guo, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814287/
https://www.ncbi.nlm.nih.gov/pubmed/36697609
http://dx.doi.org/10.1038/s42004-022-00756-7
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author Guo, Huijuan
author_facet Guo, Huijuan
author_sort Guo, Huijuan
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description The role of selenium in proteins and nucleic acids is well-established, but the pathway for incorporating selenium into small molecules remains unknown. Now, using bioinformatics tools, a selenium-incorporating gene cluster is discovered from immense genomic data, leading to the identification of selenoneine from microorganisms and the elucidation of a selenium incorporation pathway.
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spelling pubmed-98142872023-01-10 Selenium-containing small molecules Guo, Huijuan Commun Chem Research Highlight The role of selenium in proteins and nucleic acids is well-established, but the pathway for incorporating selenium into small molecules remains unknown. Now, using bioinformatics tools, a selenium-incorporating gene cluster is discovered from immense genomic data, leading to the identification of selenoneine from microorganisms and the elucidation of a selenium incorporation pathway. Nature Publishing Group UK 2022-10-28 /pmc/articles/PMC9814287/ /pubmed/36697609 http://dx.doi.org/10.1038/s42004-022-00756-7 Text en © Springer Nature Limited 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Highlight
Guo, Huijuan
Selenium-containing small molecules
title Selenium-containing small molecules
title_full Selenium-containing small molecules
title_fullStr Selenium-containing small molecules
title_full_unstemmed Selenium-containing small molecules
title_short Selenium-containing small molecules
title_sort selenium-containing small molecules
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814287/
https://www.ncbi.nlm.nih.gov/pubmed/36697609
http://dx.doi.org/10.1038/s42004-022-00756-7
work_keys_str_mv AT guohuijuan seleniumcontainingsmallmolecules

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