Intrastrand backbone-nucleobase interactions stabilize unwound right-handed helical structures of heteroduplexes of L-aTNA/RNA and SNA/RNA

Xeno nucleic acids, which are synthetic analogues of natural nucleic acids, have potential for use in nucleic acid drugs and as orthogonal genetic biopolymers and prebiotic precursors. Although few acyclic nucleic acids can stably bind to RNA and DNA, serinol nucleic acid (SNA) and L-threoninol nucl...

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Detalles Bibliográficos
Autores principales: Kamiya, Yukiko, Satoh, Tadashi, Kodama, Atsuji, Suzuki, Tatsuya, Murayama, Keiji, Kashida, Hiromu, Uchiyama, Susumu, Kato, Koichi, Asanuma, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814321/
https://www.ncbi.nlm.nih.gov/pubmed/36703369
http://dx.doi.org/10.1038/s42004-020-00400-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814321/
https://www.ncbi.nlm.nih.gov/pubmed/36703369
http://dx.doi.org/10.1038/s42004-020-00400-2

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