CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs

BACKGROUND: Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. Eliminating the risk factor of malignant cell transformation is essential for ensuring the safety of such cells. This study was aimed at assessing and m...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakuma, Kensuke, Tsubooka-Yamazoe, Noriko, Hashimoto, Kiyohiro, Sakai, Nozomu, Asano, Shinya, Watanabe-Matsumoto, Saori, Watanabe, Takeshi, Saito, Bunnai, Matsumoto, Hirokazu, Ueno, Hikaru, Ito, Ryo, Toyoda, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814340/
https://www.ncbi.nlm.nih.gov/pubmed/36600289
http://dx.doi.org/10.1186/s13287-022-03220-4

Ejemplares similares

Ejemplares similares