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Hepatocellular carcinoma detection via targeted enzymatic methyl sequencing of plasma cell-free DNA

BACKGROUND: Epigenetic variants carried by circulating tumor DNA can be used as biomarkers for early detection of hepatocellular carcinoma (HCC) by noninvasive liquid biopsy. However, traditional methylation analysis method, bisulfite sequencing, with disadvantages of severe DNA damage, is limited i...

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Detalles Bibliográficos
Autores principales:	Guo, Ping, Zheng, Hailing, Li, Yihan, Li, Yuntong, Xiao, Yue, Zheng, Jin, Zhu, Xingqiang, Xu, Huan, He, Zhi, Zhang, Qian, Chen, Jinchun, Qiu, Mingshan, Jiang, Min, Liu, Pingguo, Chen, Hongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814445/ https://www.ncbi.nlm.nih.gov/pubmed/36600275 http://dx.doi.org/10.1186/s13148-022-01420-6

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