Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

BACKGROUND: Observational studies have linked childhood obesity with elevated risk of colorectal cancer; however, it is unclear if this association is causal or independent from the effects of obesity in adulthood on colorectal cancer risk. METHODS: We conducted Mendelian randomization (MR) analyses...

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Detalles Bibliográficos
Autores principales: Papadimitriou, Nikos, Bull, Caroline J., Jenab, Mazda, Hughes, David J., Bell, Joshua A., Sanderson, Eleanor, Timpson, Nicholas J., Smith, George Davey, Albanes, Demetrius, Campbell, Peter T., Küry, Sébastien, Le Marchand, Loic, Ulrich, Cornelia M., Visvanathan, Kala, Figueiredo, Jane C., Newcomb, Polly A., Pai, Rish K., Peters, Ulrike, Tsilidis, Kostas K., Boer, Jolanda M. A., Vincent, Emma E., Mariosa, Daniela, Gunter, Marc J., Richardson, Tom G., Murphy, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814460/
https://www.ncbi.nlm.nih.gov/pubmed/36600297
http://dx.doi.org/10.1186/s12916-022-02702-9

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