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Bibliometric insights from publications on subchondral bone research in osteoarthritis
Background: The role of subchondral bone in the pathogenesis of osteoarthritis has received continuous attention worldwide. To date, no comprehensive bibliometric analysis of this topic has been carried out. The purpose of this study was to investigate the knowledge landscape, hot spots, and researc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814489/ https://www.ncbi.nlm.nih.gov/pubmed/36620224 http://dx.doi.org/10.3389/fphys.2022.1095868 |
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author | Wen, Pengfei Liu, Rui Wang, Jun Wang, Yakang Song, Wei Zhang, Yumin |
author_facet | Wen, Pengfei Liu, Rui Wang, Jun Wang, Yakang Song, Wei Zhang, Yumin |
author_sort | Wen, Pengfei |
collection | PubMed |
description | Background: The role of subchondral bone in the pathogenesis of osteoarthritis has received continuous attention worldwide. To date, no comprehensive bibliometric analysis of this topic has been carried out. The purpose of this study was to investigate the knowledge landscape, hot spots, and research trends in subchondral bone research through bibliometrics. Methods: Web of Science Core Collection database was used to collect articles and reviews on subchondral bone in osteoarthritis published between 2003 and 2022. CiteSpace, VOSviewer, Scimago Graphica, and a bibliometric online analysis platform (http://bibliometric.com/) were used to visualize the knowledge network of countries, institutions, authors, references, and keywords in this field. Both curve fitting and statistical plotting were performed using OriginPro, while correlation analysis was done using SPSS. Results: A total of 3,545 articles and reviews were included. The number of publications on subchondral bone showed an exponential growth trend. The US produced the most (980), followed by China (862) and the United Kingdom (364). Scientific output and gross domestic product were significantly correlated (r = .948, p < .001). The University of California System and Professor Pelletier Jean-Pierre were the most prolific institutions and influential authors, respectively. The most active and influential journal for subchondral bone research was Osteoarthritis and Cartilage. The majority of papers were financed by NSFC (474, 13.4%), followed by HHS (445, 12.6%), and NIH (438, 12.4%). In recent years, hot keywords have focused on the research of pathomechanisms (e.g., inflammation, apoptosis, pathogenesis, cartilage degeneration/repair, angiogenesis, TGF beta) and therapeutics (e.g., regeneration, stromal cell, mesenchymal stem cell). Conclusion: Subchondral bone research in osteoarthritis is flourishing. Current topics and next research trends would be centered on the pathomechanisms of cellular and molecular interactions in the subchondral bone microenvironment in the development of osteoarthritis and the exploration of targeted treatment medicines for the altered subchondral bone microenvironment. |
format | Online Article Text |
id | pubmed-9814489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98144892023-01-06 Bibliometric insights from publications on subchondral bone research in osteoarthritis Wen, Pengfei Liu, Rui Wang, Jun Wang, Yakang Song, Wei Zhang, Yumin Front Physiol Physiology Background: The role of subchondral bone in the pathogenesis of osteoarthritis has received continuous attention worldwide. To date, no comprehensive bibliometric analysis of this topic has been carried out. The purpose of this study was to investigate the knowledge landscape, hot spots, and research trends in subchondral bone research through bibliometrics. Methods: Web of Science Core Collection database was used to collect articles and reviews on subchondral bone in osteoarthritis published between 2003 and 2022. CiteSpace, VOSviewer, Scimago Graphica, and a bibliometric online analysis platform (http://bibliometric.com/) were used to visualize the knowledge network of countries, institutions, authors, references, and keywords in this field. Both curve fitting and statistical plotting were performed using OriginPro, while correlation analysis was done using SPSS. Results: A total of 3,545 articles and reviews were included. The number of publications on subchondral bone showed an exponential growth trend. The US produced the most (980), followed by China (862) and the United Kingdom (364). Scientific output and gross domestic product were significantly correlated (r = .948, p < .001). The University of California System and Professor Pelletier Jean-Pierre were the most prolific institutions and influential authors, respectively. The most active and influential journal for subchondral bone research was Osteoarthritis and Cartilage. The majority of papers were financed by NSFC (474, 13.4%), followed by HHS (445, 12.6%), and NIH (438, 12.4%). In recent years, hot keywords have focused on the research of pathomechanisms (e.g., inflammation, apoptosis, pathogenesis, cartilage degeneration/repair, angiogenesis, TGF beta) and therapeutics (e.g., regeneration, stromal cell, mesenchymal stem cell). Conclusion: Subchondral bone research in osteoarthritis is flourishing. Current topics and next research trends would be centered on the pathomechanisms of cellular and molecular interactions in the subchondral bone microenvironment in the development of osteoarthritis and the exploration of targeted treatment medicines for the altered subchondral bone microenvironment. Frontiers Media S.A. 2022-12-22 /pmc/articles/PMC9814489/ /pubmed/36620224 http://dx.doi.org/10.3389/fphys.2022.1095868 Text en Copyright © 2022 Wen, Liu, Wang, Wang, Song and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Wen, Pengfei Liu, Rui Wang, Jun Wang, Yakang Song, Wei Zhang, Yumin Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title | Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title_full | Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title_fullStr | Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title_full_unstemmed | Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title_short | Bibliometric insights from publications on subchondral bone research in osteoarthritis |
title_sort | bibliometric insights from publications on subchondral bone research in osteoarthritis |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814489/ https://www.ncbi.nlm.nih.gov/pubmed/36620224 http://dx.doi.org/10.3389/fphys.2022.1095868 |
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