MS-RIDD paves the way toward routine double bond localization in mass spectrometry-based lipidomics

Pinpointing double bond (C=C) positions in native lipid extracts is beyond the capabilities of standard mass spectrometry-based approaches. This article highlights a novel untargeted workflow supported by the open-source software MS-RIDD, that allows for semi-automated annotation of C=C locations wi...

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Detalles Bibliográficos
Autores principales: Lamp, Leonida Marion, Hartler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814534/
https://www.ncbi.nlm.nih.gov/pubmed/36697946
http://dx.doi.org/10.1038/s42004-022-00805-1
Descripción
Sumario:Pinpointing double bond (C=C) positions in native lipid extracts is beyond the capabilities of standard mass spectrometry-based approaches. This article highlights a novel untargeted workflow supported by the open-source software MS-RIDD, that allows for semi-automated annotation of C=C locations with high confidence.

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