Actinomycetes-derived imine reductases with a preference towards bulky amine substrates

Since imine reductases (IREDs) were reported to catalyze the reductive amination reactions, they became particularly attractive for producing chiral amines. Though diverse ketones and aldehydes have been proved to be excellent substrates of IREDs, bulky amines have been rarely transformed. Here we r...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Li, Xin, Chen, Rongchang, Tan, Xianwei, Liu, Xiongduo, Ma, Yaqing, Zhu, Fangfang, An, Chunyan, Wei, Guangzheng, Yao, Yongpeng, Yang, Lujia, Zhang, Peng, Wu, Qiaqing, Sun, Zhoutong, Wang, Bin-Gui, Gao, Shu-Shan, Cui, Chengsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814587/
https://www.ncbi.nlm.nih.gov/pubmed/36697820
http://dx.doi.org/10.1038/s42004-022-00743-y

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