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Quantification of amyloid fibril polymorphism by nano-morphometry reveals the individuality of filament assembly
Amyloid fibrils are highly polymorphic structures formed by many different proteins. They provide biological function but also abnormally accumulate in numerous human diseases. The physicochemical principles of amyloid polymorphism are not understood due to lack of structural insights at the single-...
Autores principales: | Aubrey, Liam D., Blakeman, Ben J. F., Lutter, Liisa, Serpell, Christopher J., Tuite, Mick F., Serpell, Louise C., Xue, Wei-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814634/ https://www.ncbi.nlm.nih.gov/pubmed/36703355 http://dx.doi.org/10.1038/s42004-020-00372-3 |
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