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Open questions on the transfer of chirality
The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discuss...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814639/ https://www.ncbi.nlm.nih.gov/pubmed/36697611 http://dx.doi.org/10.1038/s42004-021-00614-y |
Sumario: | The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discusses possible approaches for the rational development of enantioselective catalysts. |
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