Open questions on the transfer of chirality

The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discuss...

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Detalles Bibliográficos
Autor principal: Reid, Jolene P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814639/
https://www.ncbi.nlm.nih.gov/pubmed/36697611
http://dx.doi.org/10.1038/s42004-021-00614-y
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author Reid, Jolene P.
author_facet Reid, Jolene P.
author_sort Reid, Jolene P.
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description The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discusses possible approaches for the rational development of enantioselective catalysts.
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spelling pubmed-98146392023-01-10 Open questions on the transfer of chirality Reid, Jolene P. Commun Chem Comment The transfer of chiral information from optically pure reaction components to products can generate enantiomerically-enriched molecules, but the control of stereochemistry often proves challenging. Here, the author highlights how our fundamental understanding of stereocontrol has evolved and discusses possible approaches for the rational development of enantioselective catalysts. Nature Publishing Group UK 2021-12-09 /pmc/articles/PMC9814639/ /pubmed/36697611 http://dx.doi.org/10.1038/s42004-021-00614-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Reid, Jolene P.
Open questions on the transfer of chirality
title Open questions on the transfer of chirality
title_full Open questions on the transfer of chirality
title_fullStr Open questions on the transfer of chirality
title_full_unstemmed Open questions on the transfer of chirality
title_short Open questions on the transfer of chirality
title_sort open questions on the transfer of chirality
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814639/
https://www.ncbi.nlm.nih.gov/pubmed/36697611
http://dx.doi.org/10.1038/s42004-021-00614-y
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