Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate

Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affec...

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Detalles Bibliográficos
Autores principales: Kumar, Sachin, Parekh, Sapun H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814659/
https://www.ncbi.nlm.nih.gov/pubmed/36703309
http://dx.doi.org/10.1038/s42004-019-0254-9
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author Kumar, Sachin
Parekh, Sapun H.
author_facet Kumar, Sachin
Parekh, Sapun H.
author_sort Kumar, Sachin
collection PubMed
description Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function.
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spelling pubmed-98146592023-01-10 Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate Kumar, Sachin Parekh, Sapun H. Commun Chem Review Article Graphene, an allotrope of carbon, consists of a single layer of carbon atoms with uniquely tuneable properties. As such, graphene-based materials (GBMs) have gained interest for tissue engineering applications. GBMs are often discussed in the context of how different physicochemical properties affect cell physiology, without explicitly considering the impact of adsorbed proteins. Establishing a relationship between graphene properties, adsorbed proteins, and cell response is necessary as these proteins provide the surface upon which cells attach and grow. This review highlights the molecular adsorption of proteins on different GBMs, protein structural changes, and the connection to cellular function. Nature Publishing Group UK 2020-01-20 /pmc/articles/PMC9814659/ /pubmed/36703309 http://dx.doi.org/10.1038/s42004-019-0254-9 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Kumar, Sachin
Parekh, Sapun H.
Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title_full Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title_fullStr Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title_full_unstemmed Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title_short Linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
title_sort linking graphene-based material physicochemical properties with molecular adsorption, structure and cell fate
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814659/
https://www.ncbi.nlm.nih.gov/pubmed/36703309
http://dx.doi.org/10.1038/s42004-019-0254-9
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