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Structure-guided product determination of the bacterial type II diterpene synthase Tpn2

A grand challenge in terpene synthase (TS) enzymology is the ability to predict function from protein sequence. Given the limited number of characterized bacterial TSs and significant sequence diversities between them and their eukaryotic counterparts, this is currently impossible. To contribute tow...

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Detalles Bibliográficos
Autores principales: Stowell, Emma A., Ehrenberger, Michelle A., Lin, Ya-Lin, Chang, Chin-Yuan, Rudolf, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814783/
https://www.ncbi.nlm.nih.gov/pubmed/36698006
http://dx.doi.org/10.1038/s42004-022-00765-6