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NiH-catalyzed anti-Markovnikov hydroamidation of unactivated alkenes with 1,4,2-dioxazol-5-ones for the direct synthesis of N-alkyl amides

The addition of a nitrogen-based functional group to alkenes via a direct catalytic method is an attractive way of synthesizing value-added amides. The regioselective hydroamidation of unactivated alkenes is considered one of the easiest ways to achieve this goal. Herein, we report the NiH-catalyzed...

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Detalles Bibliográficos
Autores principales: Du, Bingnan, Chan, Chun-Ming, Ouyang, Yuxin, Chan, Kalok, Lin, Zhenyang, Yu, Wing-Yiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814879/
https://www.ncbi.nlm.nih.gov/pubmed/36697972
http://dx.doi.org/10.1038/s42004-022-00791-4

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