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Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection

Acellularized nerve allografts (ANAs) have been developed as substitutes for nerve autograft to promote nerve regeneration after surgical repair. In this video, the authors demonstrate operative techniques for using ANAs to repair potentially functional nerve fascicles during tumor resection. A 67-y...

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Detalles Bibliográficos
Autores principales: Miranda, Stephen P., Nguyen, Jessica, Gu, Ben J., Ali, Zarina S., Zager, Eric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815229/
https://www.ncbi.nlm.nih.gov/pubmed/36628089
http://dx.doi.org/10.3171/2022.10.FOCVID22101
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author Miranda, Stephen P.
Nguyen, Jessica
Gu, Ben J.
Ali, Zarina S.
Zager, Eric L.
author_facet Miranda, Stephen P.
Nguyen, Jessica
Gu, Ben J.
Ali, Zarina S.
Zager, Eric L.
author_sort Miranda, Stephen P.
collection PubMed
description Acellularized nerve allografts (ANAs) have been developed as substitutes for nerve autograft to promote nerve regeneration after surgical repair. In this video, the authors demonstrate operative techniques for using ANAs to repair potentially functional nerve fascicles during tumor resection. A 67-year-old female with schwannomatosis requested resection of a painful enlarging mass of the left ulnar nerve proximal to the elbow. During surgery, neuromonitoring suggested that fascicles entering the tumor could be functional. Therefore, nerve allograft was used to repair the transected fascicles. The patient recovered with full strength and sensation in the ulnar distribution, with resolution of her preoperative symptoms. The video can be found here: https://stream.cadmore.media/r10.3171/2022.10.FOCVID22101
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spelling pubmed-98152292023-01-09 Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection Miranda, Stephen P. Nguyen, Jessica Gu, Ben J. Ali, Zarina S. Zager, Eric L. Neurosurg Focus Video Article Acellularized nerve allografts (ANAs) have been developed as substitutes for nerve autograft to promote nerve regeneration after surgical repair. In this video, the authors demonstrate operative techniques for using ANAs to repair potentially functional nerve fascicles during tumor resection. A 67-year-old female with schwannomatosis requested resection of a painful enlarging mass of the left ulnar nerve proximal to the elbow. During surgery, neuromonitoring suggested that fascicles entering the tumor could be functional. Therefore, nerve allograft was used to repair the transected fascicles. The patient recovered with full strength and sensation in the ulnar distribution, with resolution of her preoperative symptoms. The video can be found here: https://stream.cadmore.media/r10.3171/2022.10.FOCVID22101 American Association of Neurological Surgeons 2023-01-01 /pmc/articles/PMC9815229/ /pubmed/36628089 http://dx.doi.org/10.3171/2022.10.FOCVID22101 Text en © 2023, The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the CC BY license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Miranda, Stephen P.
Nguyen, Jessica
Gu, Ben J.
Ali, Zarina S.
Zager, Eric L.
Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title_full Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title_fullStr Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title_full_unstemmed Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title_short Allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
title_sort allograft nerve repair to prevent sensorimotor loss after nerve sheath tumor resection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815229/
https://www.ncbi.nlm.nih.gov/pubmed/36628089
http://dx.doi.org/10.3171/2022.10.FOCVID22101
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