Cargando…

Total synthesis of justicidin B, justicidin E, and taiwanin C: A general and flexible approach toward the synthesis of natural arylnaphthalene lactone lignans

Lignans are widely present in traditional medicinal plants. Many natural arylnaphthalene lactone lignans (NALLs) isolated from the genera Justicia, Haplophyllum, and Phyllanthus possess interesting biological activities. Herein, we report a general strategy for the total synthesis of this kind of li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Kai, Sun, Yucui, Xu, Yiren, Hu, Wen, Ma, Ying, Lu, Yi, Chen, Wen, Zhang, Hongbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815507/ https://www.ncbi.nlm.nih.gov/pubmed/36618865 http://dx.doi.org/10.3389/fchem.2022.1103554

Ejemplares similares

Justicidin B: A Promising Bioactive Lignan †
por: Hemmati, Shiva, et al.
Publicado: (2016)

Transition Metal-Mediated Annulation Approaches for Synthesis of Arylnaphthalene Lignan Lactones
por: Park, Sooyoung, et al.
Publicado: (2020)

Linum narbonense: A new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B
por: Ionkova, Iliana, et al.
Publicado: (2013)

New Insight into Justicidin B Pathway and Production in Linum austriacum
por: Mascheretti, Iride, et al.
Publicado: (2021)

Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei
por: Ren, Yulin, et al.
Publicado: (2014)

A Novel Antiplatelet Aggregation Target of Justicidin B Obtained From Rostellularia Procumbens (L.) Nees
por: Yang, Yan-Fang, et al.
Publicado: (2019)

Justicidin A Reduces β-Amyloid via Inhibiting Endocytosis of β-Amyloid Precursor Protein
por: Chun, Yoon Sun, et al.
Publicado: (2019)

Total Synthesis of Lignan Lactone (–)-Hinokinin
por: Zhou, Qi-Long, et al.
Publicado: (2015)

Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery
por: Zhao, Chuang, et al.
Publicado: (2018)

Intramolecular Dehydro-Diels–Alder Reaction Affords Selective Entry to Arylnaphthalene or Aryldihydronaphthalene Lignans
por: Kocsis, Laura S., et al.
Publicado: (2014)

Differential modulation of Bax/Bcl-2 ratio and onset of caspase-3/7 activation induced by derivatives of Justicidin B in human melanoma cells A375
por: Al-Qathama, Aljawharah, et al.
Publicado: (2017)

6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca(2+) Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells
por: Luo, Jiaoyang, et al.
Publicado: (2018)

Ipso-Type Regiocontrolled Benzannulation for the Synthesis of Uniquely Substituted α-Arylnaphthalenes: Application to the First Total Synthesis of Chaihunaphthone
por: Moriguchi, Kento, et al.
Publicado: (2021)

Evaluation and Structure-Activity Relationship Analysis of a New Series of Arylnaphthalene lignans as Potential Anti-Tumor Agents
por: Luo, Jiaoyang, et al.
Publicado: (2014)

LC–ESI–FT–MS(n) Metabolite Profiling of Symphytum officinale L. Roots Leads to Isolation of Comfreyn A, an Unusual Arylnaphthalene Lignan
por: D’Urso, Gilda, et al.
Publicado: (2020)

Advances in the Synthesis of Lignan Natural Products
por: Fang, Xianhe, et al.
Publicado: (2018)

Total synthesis of the antibacterial polyketide natural product thailandamide lactone
por: Sharma, Himangshu, et al.
Publicado: (2022)

Pot and time economies in the total synthesis of Corey lactone
por: Umekubo, Nariyoshi, et al.
Publicado: (2019)

Atropostatin: Design and Total Synthesis of an Atropisomeric Lactone–Atorvastatin Prodrug
por: Pecorari, Daniel, et al.
Publicado: (2023)

Synthesis of the Tetracyclic Framework of Polycyclic Spiro Lignan Natural Products
por: Ali, Ghada, et al.
Publicado: (2020)

Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon
por: Hu, Mingyue, et al.
Publicado: (2023)

Biocatalytic synthesis of lactones and lactams
por: Hollmann, Frank, et al.
Publicado: (2018)

Purity Assessment of Aryltetralin Lactone Lignans by Quantitative (1)H Nuclear Magnetic Resonance
por: Sun, Yan-Jun, et al.
Publicado: (2015)

Lactones in the Synthesis of Prostaglandins and Prostaglandin Analogs
por: Tănase, Constantin, et al.
Publicado: (2021)

Total Synthesis of Hemerocallisamine I Paved by Gram-Scale Synthesis of (2S,4S)-4-Hydroxyglutamic Acid Lactone
por: Pinčeková, Lucia, et al.
Publicado: (2023)

Synthesis of 3,4-Dibenzyltetrahydrofuran Lignans (9,9′-Epoxylignanes)
por: Pohjoispää, Monika, et al.
Publicado: (2013)

Synthesis of l-Ascorbic Acid Lactone Derivatives
por: Shao, Li-Dong, et al.
Publicado: (2014)

Taiwanin E Induces Cell Cycle Arrest and Apoptosis in Arecoline/4-NQO-Induced Oral Cancer Cells Through Modulation of the ERK Signaling Pathway
por: Wang, Shih-Hao, et al.
Publicado: (2019)

Lactones 41.† Synthesis and Microbial Hydroxylation of Unsaturated Terpenoid Lactones with p-Menthane Ring Systems
por: Grudniewska, Aleksandra, et al.
Publicado: (2013)

Recent Developments in Lactone Monomers and Polymer Synthesis and Application
por: Bińczak, Jakub, et al.
Publicado: (2021)

Synthesis of Macrocyclic Lactones and Dilactones Using Olive Oil
por: Rana, Rohit, et al.
Publicado: (2021)

Synthesis of aromatic lactone analogues of Lipoxin A4
por: Ismael, Aya, et al.
Publicado: (2022)

Modular Synthesis and Biological Investigation of 5-Hydroxymethyl Dibenzyl Butyrolactones and Related Lignans
por: Davidson, Samuel J., et al.
Publicado: (2018)

A sterically encumbered photoredox catalyst enables the unified synthesis of the classical lignan family of natural products
por: Alfonzo, Edwin, et al.
Publicado: (2019)

Lignans
por: Barker, David
Publicado: (2019)

Asymmetric total synthesis of four bioactive lignans using donor–acceptor cyclopropanes and bioassay of (−)- and (+)-niranthin against hepatitis B and influenza viruses
por: Ota, Ryotaro, et al.
Publicado: (2022)

Towards the total synthesis of keramaphidin B
por: Jakubec, Pavol, et al.
Publicado: (2016)

Studies Directed towards the Synthesis of the Acridone Family of Natural Products: Total Synthesis of Acronycines and Atalaphyllidines
por: Mandal, Tirtha, et al.
Publicado: (2021)

Homoserine Lactone as a Structural Key Element for the Synthesis of Multifunctional Polymers
por: Marquardt, Fabian, et al.
Publicado: (2017)

Synthesis and Biotransformation of Bicyclic Unsaturated Lactones with Three or Four Methyl Groups
por: Wińska, Katarzyna, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1ccqrgis12gguvtromqaou9qhi