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Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations

OBJECTIVES: To evaluate the frequency and risk of malignancy of TSHRpI568T mutations discovered in indeterminate thyroid nodules (ITN) within the Veracyte CLIA laboratory undergoing Afirma(®) Genomic Sequencing Classifier (GSC) testing, and to evaluate a broader cohort of TSHR variants and their cat...

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Detalles Bibliográficos
Autores principales: Whitmer, Dorota, Phay, John E., Holt, Shelby, O’Donnell, Benjamin, Nguyen, Jay, Joseph, Dennis, Chi, Anthony, Wu, Shuyang, Hao, Yangyang, Huang, Jing, Klopper, Joshua P., Kloos, Richard T., Kennedy, Giulia C., Shin, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815553/
https://www.ncbi.nlm.nih.gov/pubmed/36619548
http://dx.doi.org/10.3389/fendo.2022.1073592

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