Cargando…
The structure of the human LACTB filament reveals the mechanisms of assembly and membrane binding
Mitochondria are complex organelles that play a central role in metabolism. Dynamic membrane-associated processes regulate mitochondrial morphology and bioenergetics in response to cellular demand. In tumor cells, metabolic reprogramming requires active mitochondrial metabolism for providing key met...
Autores principales: | Bennett, Jeremy A., Steward, Lottie R., Rudolph, Johannes, Voss, Adam P., Aydin, Halil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815587/ https://www.ncbi.nlm.nih.gov/pubmed/36534696 http://dx.doi.org/10.1371/journal.pbio.3001899 |
Ejemplares similares
-
Unveiling the Function of the Mitochondrial Filament-Forming Protein LACTB in Lipid Metabolism and Cancer
por: Cascone, Annunziata, et al.
Publicado: (2022) -
Targeted Nanotherapeutics Using LACTB Gene Therapy Against Melanoma
por: Liu, Jinlu, et al.
Publicado: (2021) -
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway
por: Xu, Yihui, et al.
Publicado: (2022) -
LACTB, a Metabolic Therapeutic Target in Clinical Cancer Application
por: Li, Xiaohua, et al.
Publicado: (2022) -
Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer
por: Yu, J, et al.
Publicado: (2016)