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Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study

INTRODUCTION: Our present study set out to investigate the instant state of the prefrontal cortex (PFC) in healthy subjects before and after placement in the -12°head-down tilt (HDT) position in order to explore the mechanism behind the low-dissipation optimization state of the PFC. METHODS: 40 youn...

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Autores principales: Lun, Tingting, Wang, Dexin, Li, Li, Zhou, Junliang, Zhao, Yunxuan, Chen, Yuecai, Yin, Xuntao, Ou, Shanxing, Yu, Jin, Song, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815614/
https://www.ncbi.nlm.nih.gov/pubmed/36619014
http://dx.doi.org/10.3389/fpsyg.2022.1051256
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author Lun, Tingting
Wang, Dexin
Li, Li
Zhou, Junliang
Zhao, Yunxuan
Chen, Yuecai
Yin, Xuntao
Ou, Shanxing
Yu, Jin
Song, Rong
author_facet Lun, Tingting
Wang, Dexin
Li, Li
Zhou, Junliang
Zhao, Yunxuan
Chen, Yuecai
Yin, Xuntao
Ou, Shanxing
Yu, Jin
Song, Rong
author_sort Lun, Tingting
collection PubMed
description INTRODUCTION: Our present study set out to investigate the instant state of the prefrontal cortex (PFC) in healthy subjects before and after placement in the -12°head-down tilt (HDT) position in order to explore the mechanism behind the low-dissipation optimization state of the PFC. METHODS: 40 young, right-handed healthy subjects (male: female = 20: 20) were enrolled in this study. Three resting state positions, 0°initial position, -12°HDT position, and 0°rest position were sequentially tested, each for 10 minutes. A continuous-wave functional near-infrared spectroscopy (fNIRS) instrument was used to assess the resting state hemodynamic data of the PFC. After preprocessing the hemodynamics data, we evaluated changes in resting-state functional connectivity (rsFC) level and beta values of PFC. The subjective visual analogue scale (VAS) was applied before and after the experiment. The presence of sleep changes or adverse reactions were also recorded. RESULTS: Pairwise comparisons of the concentrations of oxyhemoglobin (HbO), deoxyhemoglobin (HbR), and hemoglobin (HbT) revealed significant differences in the aforementioned positions. Specifically, the average rsFC of PFC showed a gradual increase throughout the whole process. In addition, based on graph theory, the topological properties of brain network, such as small-world network and nodal degree centrality were analyzed. The results show that global efficiency and small-world sigma (σ) value were differences between 0°initial and 0°rest. DISCUSSION: In this study, placement in the -12°HDT had a significant effect on PFC function, mainly manifested as self-inhibition, decreased concentration of HbO in the PFC, and improved rsFC, which may provide ideas to the understanding and explanation of neurological diseases.
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spelling pubmed-98156142023-01-06 Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study Lun, Tingting Wang, Dexin Li, Li Zhou, Junliang Zhao, Yunxuan Chen, Yuecai Yin, Xuntao Ou, Shanxing Yu, Jin Song, Rong Front Psychol Psychology INTRODUCTION: Our present study set out to investigate the instant state of the prefrontal cortex (PFC) in healthy subjects before and after placement in the -12°head-down tilt (HDT) position in order to explore the mechanism behind the low-dissipation optimization state of the PFC. METHODS: 40 young, right-handed healthy subjects (male: female = 20: 20) were enrolled in this study. Three resting state positions, 0°initial position, -12°HDT position, and 0°rest position were sequentially tested, each for 10 minutes. A continuous-wave functional near-infrared spectroscopy (fNIRS) instrument was used to assess the resting state hemodynamic data of the PFC. After preprocessing the hemodynamics data, we evaluated changes in resting-state functional connectivity (rsFC) level and beta values of PFC. The subjective visual analogue scale (VAS) was applied before and after the experiment. The presence of sleep changes or adverse reactions were also recorded. RESULTS: Pairwise comparisons of the concentrations of oxyhemoglobin (HbO), deoxyhemoglobin (HbR), and hemoglobin (HbT) revealed significant differences in the aforementioned positions. Specifically, the average rsFC of PFC showed a gradual increase throughout the whole process. In addition, based on graph theory, the topological properties of brain network, such as small-world network and nodal degree centrality were analyzed. The results show that global efficiency and small-world sigma (σ) value were differences between 0°initial and 0°rest. DISCUSSION: In this study, placement in the -12°HDT had a significant effect on PFC function, mainly manifested as self-inhibition, decreased concentration of HbO in the PFC, and improved rsFC, which may provide ideas to the understanding and explanation of neurological diseases. Frontiers Media S.A. 2022-12-21 /pmc/articles/PMC9815614/ /pubmed/36619014 http://dx.doi.org/10.3389/fpsyg.2022.1051256 Text en Copyright © 2022 Lun, Wang, Li, Zhou, Zhao, Chen, Yin, Ou, Yu and Song. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Lun, Tingting
Wang, Dexin
Li, Li
Zhou, Junliang
Zhao, Yunxuan
Chen, Yuecai
Yin, Xuntao
Ou, Shanxing
Yu, Jin
Song, Rong
Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title_full Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title_fullStr Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title_full_unstemmed Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title_short Low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: A functional near-infrared spectroscopy study
title_sort low-dissipation optimization of the prefrontal cortex in the −12° head-down tilt position: a functional near-infrared spectroscopy study
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815614/
https://www.ncbi.nlm.nih.gov/pubmed/36619014
http://dx.doi.org/10.3389/fpsyg.2022.1051256
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