Cargando…
Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus
Viruses must balance their reliance on host cell machinery for replication while avoiding host defense. Influenza A viruses are zoonotic agents that frequently switch hosts, causing localized outbreaks with the potential for larger pandemics. The host range of influenza virus is limited by the need...
Autores principales: | Baker, Steven F., Meistermann, Helene, Tzouros, Manuel, Baker, Aaron, Golling, Sabrina, Polster, Juliane Siebourg, Ledwith, Mitchell P., Gitter, Anthony, Augustin, Angelique, Javanbakht, Hassan, Mehle, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815647/ https://www.ncbi.nlm.nih.gov/pubmed/36542656 http://dx.doi.org/10.1371/journal.pbio.3001934 |
Ejemplares similares
-
Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse
por: Chen, Zhijun, et al.
Publicado: (2009) -
An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration
por: Tanvir Rahman, M., et al.
Publicado: (2023) -
ATP reduces mitochondrial MECR protein in liver of diet-induced obese mice in mechanism of insulin resistance
por: Qian, Shengnan, et al.
Publicado: (2020) -
An experiment-informed signal transduction model for the role of the Staphylococcus aureus MecR1 protein in β-lactam resistance
por: Belluzo, Bruno S., et al.
Publicado: (2019) -
NEMix: Single-cell Nested Effects Models for Probabilistic Pathway Stimulation
por: Siebourg-Polster, Juliane, et al.
Publicado: (2015)