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Computational Drug Repurposing Approach to Identify Novel Inhibitors of ILK Protein for Treatment of Esophageal Squamous Cell Carcinoma
PURPOSE: Esophageal squamous cell cancer (ESCC) is a deadly malignant tumor characterized by an overall 5-year survival rate below 20%, with China accounting for approximately 50% of all cases worldwide. Our previous studies have demonstrated that high integrin-linked kinase (ILK) expression plays a...
Autores principales: | Liu, Juan, Ma, Xiaoli, Cao, Leiyu, Wei, Yu, Gao, Yan, Qu, Chengcheng, Maimaitiming, Nuersimanguli, Zhang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815933/ https://www.ncbi.nlm.nih.gov/pubmed/36618074 http://dx.doi.org/10.1155/2022/3658334 |
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