ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity

ATP9A, a lipid flippase of the class II P4-ATPases, is involved in cellular vesicle trafficking. Its homozygous variants are linked to neurodevelopmental disorders in humans. However, its physiological function, the underlying mechanism as well as its pathophysiological relevance in humans and anima...

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Detalles Bibliográficos
Autores principales: Meng, Tian, Chen, Xiaoting, He, Zhengjie, Huang, Haofeng, Lin, Shiyin, Liu, Kunru, Bai, Guo, Liu, Hao, Xu, Mindong, Zhuang, Haixia, Zhang, Yunlong, Waqas, Ahmed, Liu, Qian, Zhang, Chuan, Sun, Xiang-Dong, Huang, Huansen, Umair, Muhammad, Yan, Yousheng, Feng, Du
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816018/
https://www.ncbi.nlm.nih.gov/pubmed/36604604
http://dx.doi.org/10.1038/s41380-022-01940-w

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