Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia

We report a case of a 77-year-old woman with massive pulmonary embolism associated with heparin-induced thrombocytopenia. Before developing a pulmonary embolism, the patient underwent gastrectomy due to gastric cancer and received subcutaneous heparin calcium for deep venous thrombosis prophylaxis f...

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Autores principales: Miyagawa, Atsushi, Yuri, Koichi, Nakano, Mitsunori, Shinoda, Daigo, Makino, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816026/
https://www.ncbi.nlm.nih.gov/pubmed/36644263
http://dx.doi.org/10.3400/avd.cr.22-00082
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author Miyagawa, Atsushi
Yuri, Koichi
Nakano, Mitsunori
Shinoda, Daigo
Makino, Jun
author_facet Miyagawa, Atsushi
Yuri, Koichi
Nakano, Mitsunori
Shinoda, Daigo
Makino, Jun
author_sort Miyagawa, Atsushi
collection PubMed
description We report a case of a 77-year-old woman with massive pulmonary embolism associated with heparin-induced thrombocytopenia. Before developing a pulmonary embolism, the patient underwent gastrectomy due to gastric cancer and received subcutaneous heparin calcium for deep venous thrombosis prophylaxis for 5 d. Then, thrombectomy with cardiopulmonary bypass using full heparinization was successfully performed. The patient was definitively diagnosed with this condition postoperatively, based on elevated serum antibody levels, in addition to pre- and postoperative thrombocytopenia and thrombosis. Intravenous heparin therapy was switched to argatroban. Although it is uncommon, clinicians should consider this condition in patients with a history of heparin exposure.
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spelling pubmed-98160262023-01-12 Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia Miyagawa, Atsushi Yuri, Koichi Nakano, Mitsunori Shinoda, Daigo Makino, Jun Ann Vasc Dis Case Report We report a case of a 77-year-old woman with massive pulmonary embolism associated with heparin-induced thrombocytopenia. Before developing a pulmonary embolism, the patient underwent gastrectomy due to gastric cancer and received subcutaneous heparin calcium for deep venous thrombosis prophylaxis for 5 d. Then, thrombectomy with cardiopulmonary bypass using full heparinization was successfully performed. The patient was definitively diagnosed with this condition postoperatively, based on elevated serum antibody levels, in addition to pre- and postoperative thrombocytopenia and thrombosis. Intravenous heparin therapy was switched to argatroban. Although it is uncommon, clinicians should consider this condition in patients with a history of heparin exposure. Japanese College of Angiology / The Japanese Society for Vascular Surgery / Japanese Society of Phlebology 2022-12-25 /pmc/articles/PMC9816026/ /pubmed/36644263 http://dx.doi.org/10.3400/avd.cr.22-00082 Text en © 2022 The Editorial Committee of Annals of Vascular Diseases. https://creativecommons.org/licenses/by/2.5/This article is distributed under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided the credit of the original work, a link to the license, and indication of any change are properly given, and the original work is not used for commercial purposes. Remixed or transformed contributions must be distributed under the same license as the original.
spellingShingle Case Report
Miyagawa, Atsushi
Yuri, Koichi
Nakano, Mitsunori
Shinoda, Daigo
Makino, Jun
Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title_full Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title_fullStr Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title_full_unstemmed Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title_short Cardiopulmonary Bypass Surgery in a Patient with Unexpected Heparin-Induced Thrombocytopenia
title_sort cardiopulmonary bypass surgery in a patient with unexpected heparin-induced thrombocytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816026/
https://www.ncbi.nlm.nih.gov/pubmed/36644263
http://dx.doi.org/10.3400/avd.cr.22-00082
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