Effects of baclofen on insular gain anticipation in alcohol-dependent patients — a randomized, placebo-controlled, pharmaco-fMRI pilot trial

RATIONALE: One hallmark of addiction is an altered neuronal reward processing. In healthy individuals (HC), reduced activity in fronto-striatal regions including the insula has been observed when a reward anticipation task was performed repeatedly. This effect could indicate a desensitization of the...

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Detalles Bibliográficos
Autores principales: Pelz, Patricia, Genauck, Alexander, Lorenz, Robert C., Wüstenberg, Torsten, Wackerhagen, Carolin, Charlet, Katrin, Gleich, Tobias, Geisel, Olga, Heinz, Andreas, Müller, Christian A., Beck, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816215/
https://www.ncbi.nlm.nih.gov/pubmed/36538099
http://dx.doi.org/10.1007/s00213-022-06291-6

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