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Whole-genome sequencing of artificial single-nucleotide variants induced by DNA degradation in biological crime scene traces
The aim of this study was to identify artificial single-nucleotide variants (SNVs) in degraded trace DNA samples. In a preliminary study, blood samples were stored for up to 120 days and whole-genome sequencing was performed using the Snakemake workflow dna-seq-gatk-variant-calling to identify posit...
Autores principales: | Schulze Johann, Kristina, Bauer, Hannah, Wiegand, Peter, Pfeiffer, Heidi, Vennemann, Marielle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816238/ https://www.ncbi.nlm.nih.gov/pubmed/36352329 http://dx.doi.org/10.1007/s00414-022-02911-0 |
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