The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients

The precise pathogenesis of achalasia is still unclear. Neurodegenerative and/or demyelinating disorders (NDD) appear to share some common pathophysiological pathways described in achalasia such as inflammation, autoimmune, mitochondrial dysfunction, and neurodegeneration. Jerie et al. have publishe...

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Autores principales: Khoury, Salim T., Mari, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816455/
https://www.ncbi.nlm.nih.gov/pubmed/36660005
http://dx.doi.org/10.1515/tnsci-2022-0269
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author Khoury, Salim T.
Mari, Amir
author_facet Khoury, Salim T.
Mari, Amir
author_sort Khoury, Salim T.
collection PubMed
description The precise pathogenesis of achalasia is still unclear. Neurodegenerative and/or demyelinating disorders (NDD) appear to share some common pathophysiological pathways described in achalasia such as inflammation, autoimmune, mitochondrial dysfunction, and neurodegeneration. Jerie et al. have published on the October issue a prospective study assessing the prevalence of several NDD in achalasia patients. In this commentary, we shed some light on the possible link between achalasia and NDD as well as comment on the study by Jerie et al.
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spelling pubmed-98164552023-01-18 The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients Khoury, Salim T. Mari, Amir Transl Neurosci Commentary The precise pathogenesis of achalasia is still unclear. Neurodegenerative and/or demyelinating disorders (NDD) appear to share some common pathophysiological pathways described in achalasia such as inflammation, autoimmune, mitochondrial dysfunction, and neurodegeneration. Jerie et al. have published on the October issue a prospective study assessing the prevalence of several NDD in achalasia patients. In this commentary, we shed some light on the possible link between achalasia and NDD as well as comment on the study by Jerie et al. De Gruyter 2022-12-31 /pmc/articles/PMC9816455/ /pubmed/36660005 http://dx.doi.org/10.1515/tnsci-2022-0269 Text en © 2022 the author(s), published by De Gruyter https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Commentary
Khoury, Salim T.
Mari, Amir
The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title_full The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title_fullStr The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title_full_unstemmed The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title_short The possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
title_sort possible association between neurodegenerative/demyelinating neurological disorders in achalasia patients
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816455/
https://www.ncbi.nlm.nih.gov/pubmed/36660005
http://dx.doi.org/10.1515/tnsci-2022-0269
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