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Gemigliptin Alleviates Succinate-Induced Hepatic Stellate Cell Activation by Ameliorating Mitochondrial Dysfunction

BACKGROUND: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) are used clinically as oral antidiabetic agents. Although DPP-4Is are known to ameliorate liver fibrosis, the protective mechanism of DPP-4Is in liver fibrosis remains obscure. In this study, gemigliptin was used to investigate the potential of...

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Detalles Bibliográficos
Autores principales: Nguyen, Giang, Park, So Young, Do, Dinh Vinh, Choi, Dae-Hee, Cho, Eun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816499/
https://www.ncbi.nlm.nih.gov/pubmed/36377343
http://dx.doi.org/10.3803/EnM.2022.1530