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A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury

OBJECTIVE: To develop a nomogram for the prediction of tracheostomy in patients with traumatic cervical spinal cord injury (TCSCI). METHODS: A total of 689 TCSCI patients were included in our study. First, the variable selection was performed using between-group comparisons and LASSO regression anal...

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Autores principales: Jian, Yunbo, Sun, Dawei, Zhang, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Spinal Neurosurgery Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816579/
https://www.ncbi.nlm.nih.gov/pubmed/36597643
http://dx.doi.org/10.14245/ns.2244596.298
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author Jian, Yunbo
Sun, Dawei
Zhang, Zhengfeng
author_facet Jian, Yunbo
Sun, Dawei
Zhang, Zhengfeng
author_sort Jian, Yunbo
collection PubMed
description OBJECTIVE: To develop a nomogram for the prediction of tracheostomy in patients with traumatic cervical spinal cord injury (TCSCI). METHODS: A total of 689 TCSCI patients were included in our study. First, the variable selection was performed using between-group comparisons and LASSO regression analysis. Second, a multivariate logistic regression analysis (MLRA) with a step-by-step method was performed. A nomogram model was developed based on the MLRA. Finally, the model was validated on the training set and validation set. RESULTS: The nomogram prediction model incorporated 5 predictors, including smoking history, dislocation, thoracic injury, American Spinal Injury Association (ASIA) grade, and neurological level of injury (NLI). The area under curve in the training group and in the validation group were 0.883 and 0.909, respectively. The Hosmer-Lemeshow test result was p = 0.153. From the decision curve analysis curve, the model performed well and was feasible to make beneficial clinical decisions. CONCLUSION: The nomogram combining dislocation, thoracic injury, ASIA grade A, NLI, and smoking history was validated as a reliable model for the prediction of tracheostomy.
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spelling pubmed-98165792023-01-11 A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury Jian, Yunbo Sun, Dawei Zhang, Zhengfeng Neurospine Original Article OBJECTIVE: To develop a nomogram for the prediction of tracheostomy in patients with traumatic cervical spinal cord injury (TCSCI). METHODS: A total of 689 TCSCI patients were included in our study. First, the variable selection was performed using between-group comparisons and LASSO regression analysis. Second, a multivariate logistic regression analysis (MLRA) with a step-by-step method was performed. A nomogram model was developed based on the MLRA. Finally, the model was validated on the training set and validation set. RESULTS: The nomogram prediction model incorporated 5 predictors, including smoking history, dislocation, thoracic injury, American Spinal Injury Association (ASIA) grade, and neurological level of injury (NLI). The area under curve in the training group and in the validation group were 0.883 and 0.909, respectively. The Hosmer-Lemeshow test result was p = 0.153. From the decision curve analysis curve, the model performed well and was feasible to make beneficial clinical decisions. CONCLUSION: The nomogram combining dislocation, thoracic injury, ASIA grade A, NLI, and smoking history was validated as a reliable model for the prediction of tracheostomy. Korean Spinal Neurosurgery Society 2022-12 2022-12-31 /pmc/articles/PMC9816579/ /pubmed/36597643 http://dx.doi.org/10.14245/ns.2244596.298 Text en Copyright © 2022 by the Korean Spinal Neurosurgery Society https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jian, Yunbo
Sun, Dawei
Zhang, Zhengfeng
A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title_full A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title_fullStr A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title_full_unstemmed A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title_short A Nomogram Model for Prediction of Tracheostomy in Patients With Traumatic Cervical Spinal Cord Injury
title_sort nomogram model for prediction of tracheostomy in patients with traumatic cervical spinal cord injury
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816579/
https://www.ncbi.nlm.nih.gov/pubmed/36597643
http://dx.doi.org/10.14245/ns.2244596.298
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