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Suppression of chromosome instability by targeting a DNA helicase in budding yeast

Chromosome instability (CIN) is an important driver of cancer initiation, progression, drug resistance, and aging. As such, genes whose inhibition suppresses CIN are potential therapeutic targets. We report here that deletion of an accessory DNA helicase, Rrm3, suppresses high CIN caused by a wide r...

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Detalles Bibliográficos
Autores principales:	Gordon, Molly R., Zhu, Jin, Sun, Gordon, Li, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816644/ https://www.ncbi.nlm.nih.gov/pubmed/36350688 http://dx.doi.org/10.1091/mbc.E22-09-0395

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