A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients

Animal testing of cosmetic ingredients and products has been banned in the European Union since 2013. However, in Japan, the application of new quasi-drugs requires the generation of data on acute oral toxicity through animal testing. A weight of evidence approach for assessing oral toxicity was cha...

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Detalles Bibliográficos
Autores principales: Kojima, Hajime, Nakada, Tokio, Yagami, Akiko, Todo, Hiroaki, Nishimura, Jihei, Yagi, Mio, Yamamoto, Keiko, Sugiyama, Mariko, Ikarashi, Yoshiaki, Sakaguchi, Hitoshi, Yamaguchi, Masahiko, Hirota, Morihiko, Aizawa, Sakiko, Nakagawa, Shota, Hagino, Shigenobu, Hatao, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816657/
https://www.ncbi.nlm.nih.gov/pubmed/36619289
http://dx.doi.org/10.1016/j.crtox.2022.100100

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