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Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging
PURPOSE: The aim of this study was to assess carotid stiffening in a pre-hypertensive (PHT) population using ultrafast pulse wave velocity (ufPWV). METHODS: This study retrospectively enrolled 626 individuals who underwent clinical interviews, serum tests, and assessments of the systolic blood press...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Ultrasound in Medicine
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816694/ https://www.ncbi.nlm.nih.gov/pubmed/36588181 http://dx.doi.org/10.14366/usg.22039 |
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author | Ma, Xuehui Zhu, Zhengqiu Wang, Yinping Shen, Bixiao Jiang, Xuezhong Liu, Wenjun Wu, Yiyun Zou, Chong Luan, Yun Gao, Hui Huang, Hui |
author_facet | Ma, Xuehui Zhu, Zhengqiu Wang, Yinping Shen, Bixiao Jiang, Xuezhong Liu, Wenjun Wu, Yiyun Zou, Chong Luan, Yun Gao, Hui Huang, Hui |
author_sort | Ma, Xuehui |
collection | PubMed |
description | PURPOSE: The aim of this study was to assess carotid stiffening in a pre-hypertensive (PHT) population using ultrafast pulse wave velocity (ufPWV). METHODS: This study retrospectively enrolled 626 individuals who underwent clinical interviews, serum tests, and assessments of the systolic blood pressure (SBP), diastolic blood pressure (DBP), carotid intima-media thickness (cIMT), pulse wave velocity-beginning of systole (PWV-BS), and pulse wave velocity-end of systole (PWV-ES) between January 2017 and December 2021. The patients were divided into three groups according to their blood pressure (BP)—normal BP (NBP): SBP <130 mmHg and DBP <80 mmHg (n=215); PHT: 130 mmHg≤SBP<140 mmHg and/or 80 mmHg≤DBP<90 mmHg (n=119); hypertensive (HT): SBP ≥140 mmHg and/or DBP ≥90 mmHg (n=292). Correlation analyses and comparisons were performed among the groups and in the cIMT subgroups (cIMT ≥0.050 cm and <0.050 cm). RESULTS: cIMT and PWV-ES significantly differed among the BP groups (P<0.05). The BP groups had similar PWV-BS when cIMT <0.050 cm or cIMT ≥0.050 cm (all P>0.05). However, the NBP group had a notably lower PWV-ES than the PHT (P<0.001 and P=0.024) and HT (all P<0.001) groups in both cIMT categories, while the PWV-ES in the PHT group were not significantly lower than in the HT group (all P>0.05). CONCLUSION: Carotid morphological and biomechanical properties in the PHT group differed from those in the NBP group. ufPWV could be used for an early evaluation of carotid stiffening linked to pre-hypertension. |
format | Online Article Text |
id | pubmed-9816694 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Korean Society of Ultrasound in Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-98166942023-01-11 Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging Ma, Xuehui Zhu, Zhengqiu Wang, Yinping Shen, Bixiao Jiang, Xuezhong Liu, Wenjun Wu, Yiyun Zou, Chong Luan, Yun Gao, Hui Huang, Hui Ultrasonography Original Article PURPOSE: The aim of this study was to assess carotid stiffening in a pre-hypertensive (PHT) population using ultrafast pulse wave velocity (ufPWV). METHODS: This study retrospectively enrolled 626 individuals who underwent clinical interviews, serum tests, and assessments of the systolic blood pressure (SBP), diastolic blood pressure (DBP), carotid intima-media thickness (cIMT), pulse wave velocity-beginning of systole (PWV-BS), and pulse wave velocity-end of systole (PWV-ES) between January 2017 and December 2021. The patients were divided into three groups according to their blood pressure (BP)—normal BP (NBP): SBP <130 mmHg and DBP <80 mmHg (n=215); PHT: 130 mmHg≤SBP<140 mmHg and/or 80 mmHg≤DBP<90 mmHg (n=119); hypertensive (HT): SBP ≥140 mmHg and/or DBP ≥90 mmHg (n=292). Correlation analyses and comparisons were performed among the groups and in the cIMT subgroups (cIMT ≥0.050 cm and <0.050 cm). RESULTS: cIMT and PWV-ES significantly differed among the BP groups (P<0.05). The BP groups had similar PWV-BS when cIMT <0.050 cm or cIMT ≥0.050 cm (all P>0.05). However, the NBP group had a notably lower PWV-ES than the PHT (P<0.001 and P=0.024) and HT (all P<0.001) groups in both cIMT categories, while the PWV-ES in the PHT group were not significantly lower than in the HT group (all P>0.05). CONCLUSION: Carotid morphological and biomechanical properties in the PHT group differed from those in the NBP group. ufPWV could be used for an early evaluation of carotid stiffening linked to pre-hypertension. Korean Society of Ultrasound in Medicine 2023-01 2022-07-09 /pmc/articles/PMC9816694/ /pubmed/36588181 http://dx.doi.org/10.14366/usg.22039 Text en Copyright © 2023 Korean Society of Ultrasound in Medicine (KSUM) https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ma, Xuehui Zhu, Zhengqiu Wang, Yinping Shen, Bixiao Jiang, Xuezhong Liu, Wenjun Wu, Yiyun Zou, Chong Luan, Yun Gao, Hui Huang, Hui Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title | Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title_full | Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title_fullStr | Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title_full_unstemmed | Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title_short | Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
title_sort | quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816694/ https://www.ncbi.nlm.nih.gov/pubmed/36588181 http://dx.doi.org/10.14366/usg.22039 |
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