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ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells

Diabetic nephropathy (DN) is a leading cause of end-stage renal disease and continues to be a threat to patients with diabetes. Dysfunction of glomerular mesangial cells (GMCs) is the main contributing factor to glomerulosclerosis, which is a pathological feature of DN. The epigenetic factor ASH2L h...

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Detalles Bibliográficos
Autores principales: Zhong, Wen, Hong, Chen, Dong, Yejun, Li, Yuhui, Xiao, Chenxi, Liu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816940/
https://www.ncbi.nlm.nih.gov/pubmed/36553510
http://dx.doi.org/10.3390/genes13122244