PAX8 modulates the tumor microenvironment of high grade serous ovarian cancer through changes in the secretome

High grade serous ovarian cancer (HGSC) arises from the fimbriated end of the fallopian tube epithelium (FTE), and in some cases, the ovarian surface epithelium (OSE). PAX8 is a commonly used biomarker for HGSC and is expressed in ∼90% of HGSC. Although the OSE does not express PAX8, murine models o...

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Detalles Bibliográficos
Autores principales: Salvi, Amrita, Hardy, Laura R., Heath, Kimberly N., Watry, Samantha, Pergande, Melissa R., Cologna, Stephanie M., Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816987/
https://www.ncbi.nlm.nih.gov/pubmed/36586182
http://dx.doi.org/10.1016/j.neo.2022.100866

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