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Simple, Reliable Protocol for High-Yield Solubilization of Seedless Amyloid-β Monomer

[Image: see text] Self-assembly of the amyloid-β (Aβ) peptide to form toxic oligomers and fibrils is a key causal event in the onset of Alzheimer’s disease, and Aβ is the focus of intense research in neuroscience, biophysics, and structural biology aimed at therapeutic development. Due to its rapid...

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Detalles Bibliográficos
Autores principales: Taylor, Alexander I. P., Davis, Peter J., Aubrey, Liam D., White, Joshua B. R., Parton, Zoe N., Staniforth, Rosemary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817077/
https://www.ncbi.nlm.nih.gov/pubmed/36512740
http://dx.doi.org/10.1021/acschemneuro.2c00411

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