Research advances in cGAS–stimulator of interferon genes pathway and central nervous system diseases: Focus on new therapeutic approaches

Cyclic GMP–AMP synthase (cGAS), a crucial innate immune sensor, recognizes cytosolic DNA and induces stimulator of interferon genes (STING) to produce type I interferon and other proinflammatory cytokines, thereby mediating innate immune signaling. The cGAS–STING pathway is involved in the regulatio...

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Detalles Bibliográficos
Autores principales: Ding, Jiao, Dai, Yijie, Zhu, Jiahui, Fan, Xuemei, Zhang, Hao, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817143/
https://www.ncbi.nlm.nih.gov/pubmed/36618820
http://dx.doi.org/10.3389/fnmol.2022.1050837

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