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Resting time after phorbol 12-myristate 13-acetate in THP-1 derived macrophages provides a non-biased model for the study of NLRP3 inflammasome

BACKGROUND: The activation of NLRP3 inflammasome in macrophages has been proven to play a crucial role in the development of cardiovascular diseases. THP-1 monocytes can be differentiated to macrophages by incubation with phorbol-12-myristate 13-acetate (PMA), providing a suitable model for in vitro...

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Detalles Bibliográficos
Autores principales:	Giambelluca, Sonia, Ochs, Matthias, Lopez-Rodriguez, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817155/ https://www.ncbi.nlm.nih.gov/pubmed/36618426 http://dx.doi.org/10.3389/fimmu.2022.958098

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