Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2

Non-structural protein 1 (Nsp1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major virulence factor and thus an attractive drug target. The last 33 amino acids of Nsp1 have been shown to bind within the mRNA entry tunnel of the 40S ribosomal subunit, shutting off host gene ex...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Kirkpatrick, John, Lage, Susanne zur, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817231/
https://www.ncbi.nlm.nih.gov/pubmed/36610391
http://dx.doi.org/10.1016/j.str.2022.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817231/
https://www.ncbi.nlm.nih.gov/pubmed/36610391
http://dx.doi.org/10.1016/j.str.2022.12.006

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