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BETi enhance ATGL expression and its lipase activity to exert their antitumoral effects in triple-negative breast cancer (TNBC) cells

BACKGROUND: Triple-Negative Breast Cancer (TNBC) is a subtype of breast cancer that differs from other types of breast cancers in the faster spread and worse outcome. TNBC presented limited treatment options. BET (Bromodomain and extra-terminal domain) proteins are epigenetic readers that control th...

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Detalles Bibliográficos
Autores principales: Rossi, Teresa, Zamponi, Raffaella, Chirico, Mattea, Pisanu, Maria Elena, Iorio, Egidio, Torricelli, Federica, Gugnoni, Mila, Ciarrocchi, Alessia, Pistoni, Mariaelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817244/
https://www.ncbi.nlm.nih.gov/pubmed/36604676
http://dx.doi.org/10.1186/s13046-022-02571-3