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An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer
BACKGROUND: According to current guidelines, more than 70% of patients with invasive submucosal colorectal cancer (T1 CRC) undergo a radical operation with lymph node dissection, even though only ~ 10% have lymph node metastasis (LNM). Hence, there is imperative to develop biomarkers that can help r...
Autores principales: | Miyazaki, Katsuki, Wada, Yuma, Okuno, Keisuke, Murano, Tatsuro, Morine, Yuji, Ikemoto, Tetsuya, Saito, Yu, Ikematsu, Hiroaki, Kinugasa, Yusuke, Shimada, Mitsuo, Goel, Ajay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817247/ https://www.ncbi.nlm.nih.gov/pubmed/36609320 http://dx.doi.org/10.1186/s12943-022-01685-8 |
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