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“Proteotranscriptomic analysis of advanced colorectal cancer patient derived organoids for drug sensitivity prediction”

BACKGROUND: Patient-derived organoids (PDOs) from advanced colorectal cancer (CRC) patients could be a key platform to predict drug response and discover new biomarkers. We aimed to integrate PDO drug response with multi-omics characterization beyond genomics. METHODS: We generated 29 PDO lines from...

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Detalles Bibliográficos
Autores principales:	Papaccio, Federica, García-Mico, Blanca, Gimeno-Valiente, Francisco, Cabeza-Segura, Manuel, Gambardella, Valentina, Gutiérrez-Bravo, María Fernanda, Alfaro-Cervelló, Clara, Martinez-Ciarpaglini, Carolina, Rentero-Garrido, Pilar, Zúñiga-Trejos, Sheila, Carbonell-Asins, Juan Antonio, Fleitas, Tania, Roselló, Susana, Huerta, Marisol, Sánchez del Pino, Manuel M., Sabater, Luís, Roda, Desamparados, Tarazona, Noelia, Cervantes, Andrés, Castillo, Josefa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817273/ https://www.ncbi.nlm.nih.gov/pubmed/36604765 http://dx.doi.org/10.1186/s13046-022-02591-z

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